About 13 results found for searched term "EP3 antagonist 4" (0.132 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41910 | EP3 antagonist 4 | Prostaglandin Receptor |
| EP3 antagonist 4 is an EP3 antagonist, with a Ki value of 2 nM for hEP. | ||
| M8912 | ML-18 | Bombesin Receptor |
| ML18 is Bombesin receptor subtype 3 (BRS-3) antagonist (IC50 = 4.8 μM). | ||
| M10857 | MF-766 | Prostaglandin Receptor |
| MF-766 is a highly effective, selective and orally active EP4 antagonist.Ki The value is 0.23 nM. MF-766 behaves as a complete antagonist with its IC in functional detection50 1.4 nM (becomes 1.8 nM when 10% HS is present). MF-766 can be used for cancer and inflammatory disease research. | ||
| M13925 | GW 766994 | CCR |
| GW 994 | ||
| GW 766994 (GW 994) is an orally active and specific chemokine receptor-3 (CCR3) antagonist. GW 766994 has the potential for asthma and eosinophilic bronchitis research. | ||
| M21323 | ACT-660602 | CXCR |
| ACT-660602 is an oral chemokine receptor CXCR3 antagonist with an IC50 of 204 nM. It is being developed for use in autoimmune diseases. | ||
| M28807 | SHU 9119 acetate | Melanocortin Receptor |
| SHU 9119 acetate is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively. | ||
| M29125 | PD 168368 | Bombesin Receptor |
| PD 168368 is a potent, competitive, and selective neuromedin B receptor (NMB-R) antagonist with the Ki of 15–45 nM. PD 168368 is neuromedin B receptor (NMBR; IC50=96 nM) / gastrin-releasing peptide receptor (GRPR IC50=3500 nM) antagonist. PD 168368 also is a mixed FPR1/FPR2/FPR3 agonist with EC50s of 0.57, 0.24, and 2.7 nM, respectively. | ||
| M29626 | P2X3 antagonist 34 | P2 Receptor |
| P2X3 antagonist 34 is a potent, selective and orally active P2X3 homotrimeric receptor antagonist with IC50s of 25 nM, 92 nM and 126 nM for human P2X3, rat P2X3 and guinea pig P2X3 receptors, respectively. P2X3 antagonist 34 is less active against human, rat and guinea pig P2X2/3 heterotrimeric receptors. P2X3 antagonist 34 has strong anti-tussive effect. | ||
| M30242 | Methoxy-PEPy | GluR |
| Methoxy-PEPy is a potent and highly selective mGlu5 receptor antagonist with IC50 of 1 nM. IC50 value: 1 nM [1] Target: mGlu5R inhibitor Administration of [3H]methoxy-PEPy (50 microCi/kg i.v.) to mGlu5 receptor-deficient mice revealed binding at background levels in forebrain, whereas wild-type mice exhibited 14-fold higher binding in forebrain relative to cerebellum . The calcium transients stimulated by these agonists were potently inhibited by reference allosteric mGlu5 antagonists - 2-methyl-6-(phenylethynyl)pyridine (MPEP), 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) and 3-methoxy-5-(pyridine-2-ylethynyl)pyridine (methoxy-PEPy) (IC(50) ranges: 0.8-66 nM) . | ||
| M40663 | A2A receptor antagonist 3 | Adenosine Receptor |
| A2A receptor antagonist 3 is an adenosine receptor A2a antagonist with a Ki of 0.4 nM. It binds to A2b, A1, and A3 receptors with Ki values of 37, 107, and 1467 nM, respectively. | ||
| M43211 | AP 811 acetate | Others |
| AP 811 acetate is a selective atrial natriuretic peptide clearance receptor (ANP-CR, NPR3) antagonist with a Ki of 0.48 nM. | ||
| M51492 | AP 811 | Others |
| AP 811 is a selective atrial natriuretic peptide clearance receptor (ANP-CR, NPR3) antagonist with a Ki of 0.48 nM. | ||
| M53868 | SHU 9119 | Melanocortin Receptor |
| SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
